Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound.
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Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound. Descriptor: 4-[(trans-4-{[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]dec-1-ylcarbamoyl]amino}cyclohexyl)oxy]benzoic acid, Bifunctional epoxide hydrolase 2 Authors: Dunge, A, Uwangue, O, Phan, C, Bjelcic, M, Gunnarsson, J, Wehlander, G, Kack, H, Branden, G. Deposit date: 2023-10-18 Release date: 2024-08-14 Last modified: 2024-09-11 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Exploring serial crystallography for drug discovery. Iucrj, 11, 2024
结合配体的可溶性环氧化物水解酶(soluble Epoxide Hydrolase)常温和低温结构对比。结构描述:4-[(反式-4-{[(3S,5S,7S)-三环[3.3.1.1³,⁷]癸-1-基甲酰胺基]氨基}环己基)氧基]苯甲酸、双功能环氧化物水解酶2(Bifunctional epoxide hydrolase 2)。作者:Dunge, A、Uwangue, O、Phan, C、Bjelcic, M、Gunnarsson, J、Wehlander, G、Kack, H、Branden, G。提交日期:2023年10月18日,发布日期:2024年8月14日,最后修改日期:2024年9月11日。研究方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.24埃(Å)。引用文献:《用于药物发现的串行晶体学探索》(Exploring serial crystallography for drug discovery),刊载于《Iucrj》第11卷,2024年。



