tumor-associated myeloid Antigen-Presenting-Cells, version 1

Reference atlas of Monocytes, Macrophages, and Dendritic cells (myeloid professional Antigen Presenting Cells)infiltrating lung tumors (Murine KP1.9 lung adenocarcinoma) and lungs of healthy mice.ScRNA-seq data (inDrop) and cell type annotations from Zilionis et al Immunity 2019 (https://doi.org/10.1016/j.immuni.2019.03.009)Mac1 Macrophage subtype 1Mac2 Macrophage subtype 2Mac3 Macrophage subtype 3Mac4 Macrophage subtype 4Mono1 Monocyte subtype 1Mono2 Monocyte subtype 2Mono3 Monocyte subtype 3MonoDC immature Monocyte-dendritic cell stateDC1 classical Dendritic Cell subtype 1DC2 classical Dendritic Cell subtype 2DC3 classical Dendritic Cell subtype 3pDC plasmacytoid Dendritic Cell

本数据集为浸润小鼠KP1.9肺腺癌（Murine KP1.9 lung adenocarcinoma）肺部肿瘤及健康小鼠肺部的单核细胞（Monocytes）、巨噬细胞（Macrophages）与树突状细胞（Dendritic cells，髓系专职抗原呈递细胞）的参考图谱。该数据集的单细胞RNA测序（single-cell RNA sequencing, scRNA-seq）数据采用inDrop技术，细胞类型注释来自Zilionis等人2019年发表于《Immunity》的研究（https://doi.org/10.1016/j.immuni.2019.03.009）。具体细胞亚型如下：Mac1型巨噬细胞亚型1、Mac2型巨噬细胞亚型2、Mac3型巨噬细胞亚型3、Mac4型巨噬细胞亚型4、Mono1型单核细胞亚型1、Mono2型单核细胞亚型2、Mono3型单核细胞亚型3、MonoDC（未成熟单核细胞-树突状细胞状态）、DC1型经典树突状细胞亚型1、DC2型经典树突状细胞亚型2、DC3型经典树突状细胞亚型3以及pDC型浆细胞样树突状细胞（plasmacytoid Dendritic Cell）。