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The MIDOG++ dataset represents an extension of the data set used in the MIDOG 2021 and 2022 challenges. We provide region of interest images from 503 histological specimens of seven different tumor types with variable morphology: breast carcinoma, lung carcinoma, lymphosarcoma, neuroendocrine tumor, cutaneous mast cell tumor, cutaneous melanoma, and (sub)cutaneous soft tissue sarcoma. The human and canine samples were processed and stained at different human and veterinary pathology laboratories with standard H&E dye and digitized with different digital whole slide image scanners. We provide labels for 11,937 mitotic figures that have been differentiated against 14,351 imposter cells in a blinded consensus by two pathologists and a final decision by a third pathologist for disagreed labels.

MIDOG++数据集是对MIDOG 2021与2022挑战赛所用数据集的扩展。本数据集提供了503份组织学标本的感兴趣区域（Region of Interest, ROI）图像，涵盖7种形态学特征各异的肿瘤类型：乳腺癌、肺癌、淋巴肉瘤、神经内分泌肿瘤、皮肤肥大细胞瘤、皮肤黑色素瘤，以及（亚）皮下软组织肉瘤。所有人类与犬类标本均在不同的人类病理及兽医病理实验室中，采用标准苏木精-伊红（Hematoxylin and Eosin, H&E）染色剂完成处理与染色，并通过多款不同的数字全玻片扫描仪进行数字化扫描。本数据集为11937个有丝分裂象（mitotic figure）提供了标注：标注过程中需与14351个干扰细胞进行区分，由两名病理学家开展盲法共识审核；对于标注存在分歧的样本，将由第三名病理学家作出最终裁定。