Immunization with meningococcal polysaccharide-tetanus toxoid conjugate induces polysaccharide-reactive T cells in mice.
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The polysaccharide used in this study is a homopolymer of Alpha-(2 → 9)-linked sialic acid with O-acetyl groups on C-7 and/or C-8. An epitope-specific CD4+ T cell clone reacted with the H. influenza polysaccharide conjugated to Tetanus toxoid.
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2004-01-01



