Table_1_Relationships between intra-pancreatic fat deposition and lifestyle factors: a cross-sectional study.docx

AimsThe excess deposition of intra-pancreatic fat deposition (IPFD) has been reported to be associated with type 2 diabetes, chronic pancreatitis, and pancreatic ductal adenocarcinoma. In the current study, we aimed to identify a relationship between lifestyle factors and IPFD.
Materials and methods99 patients admitted to the Osaka University Hospital who had undergone abdominal computed tomography were selected. We evaluated the mean computed tomography values of the pancreas and spleen and then calculated IPFD score. Multiple regression analyses were used to assess the associations between IPFD score and lifestyle factors.
ResultsFast eating speed, late-night eating, and early morning awakening were significantly associated with a high IPFD score after adjusting for age, sex, diabetes status and Body Mass Index (p=0.04, 0.01, 0.01, respectively).
ConclusionThe current study has elucidated the significant associations of fast eating speed, late-night eating, and early morning awakening with IPFD.

研究目的：已有研究表明，胰腺内脂肪过度沉积（intra-pancreatic fat deposition, IPFD）与2型糖尿病、慢性胰腺炎及胰腺导管腺癌密切相关。本研究旨在明确生活方式因素与胰腺内脂肪沉积之间的关联。
材料与方法：选取大阪大学附属医院收治的99名接受腹部计算机断层扫描（computed tomography, CT）检查的患者作为研究对象。我们测定了胰腺与脾脏的平均CT值，并据此计算胰腺内脂肪沉积评分。采用多元回归分析评估胰腺内脂肪沉积评分与生活方式因素间的相关性。
结果：在校正年龄、性别、糖尿病患病状态及体重指数（Body Mass Index, BMI）后，进食速度快、夜间进食以及晨起早醒与较高的胰腺内脂肪沉积评分显著相关（分别对应p=0.04、0.01、0.01）。
结论：本研究阐明了进食速度快、夜间进食及晨起早醒与胰腺内脂肪沉积之间的显著关联。