DATA+STATISTICS-CMNB-CARNOSINE-PAPER.xlsx

Both intraspinal and intramuscular local administration of neurotrophic factors (NFs) have been shown to protect neural tissue after traumatic spinal cord injury (SCI). In our study, we investigated how carnosine, a natural antioxidant commonly used as a supplement by many athletes, affects the expression of brain- and glial cell line-derived NFs (BDNF, GDNF) in the neuronal and muscle microenvironment six weeks after SCI.

脊髓内与肌内局部施用神经营养因子（neurotrophic factors, NFs）已被证实可在创伤性脊髓损伤（traumatic spinal cord injury, SCI）后对神经组织起到保护作用。本研究中，我们探究了肌肽——一种被众多运动员广泛用作膳食补充剂的天然抗氧化剂——对创伤性脊髓损伤后六周神经元与肌肉微环境中脑源性神经营养因子（brain-derived neurotrophic factor, BDNF）与胶质细胞源性神经营养因子（glial cell line-derived neurotrophic factor, GDNF）表达水平的影响。