Transcriptome changes in the retinal pigment epithelial cells of Microtubule-Associated Protein 1 Light Chain 3B gene knockout mouse (LC3b-/-)

RPE cells from WT and Total RNA was isolated from WT and LC3b-/- mice were isolated by enzymatic treatment and gentle dissociation, followed by RNA extraction. RNA-sequencing by the Next-Generation Sequencing Core of the University of Pennsylvania. We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 wild type and 3 LC3b-/-