Hazard ratios and 95% confidence intervals for primary and secondary endpoints according to baseline TSAT concentrations (Cox-proportional hazard regression analysis).
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*Composite: composite of death and hospitalization.*CV mortality was sequentially adjusted for demographics (age, diabetes, underlying cardiovascular disease, and subjective global assessment score), medications (aspirin), laboratory parameters (albumin, glucose, alkaline phosphatase, and log transformed high-sensitivity C-reactive protein), and echocardiographic findings (left ventricular mass index and left ventricular ejection fraction).*CV composite was sequentially adjusted for demographics (age, systolic blood pressure, diabetes, and underlying cardiovascular disease), medications (aspirin, clopidogrel, vitamin D, and erythropoiesis-stimulating agents), laboratory parameters (calcium, glucose, potassium, log transformed ferritin, and log transformed high-sensitivity C-reactive protein), and echocardiographic findings (left ventricular mass index and left ventricular ejection fraction).*All-cause mortality was sequentially adjusted for demographics (body mass index, Charlson Comorbidity Index, and subjective global assessment score), medications (aspirin, clopidogrel, and vitamin D), laboratory parameters (alkaline phosphatase, calcium, glucose, log transformed ferritin, and log transformed high-sensitivity C-reactive protein), and echocardiographic findings (left ventricular mass index and left ventricular ejection fraction).Abbreviations: TSAT, transferrin saturation; CV, cardiovascular; HR, hazard ratio; CI, confidence interval.
*复合终点:死亡与住院的复合事件。*心血管(cardiovascular, CV)死亡率会依次校正以下变量:人口学特征(年龄、糖尿病、基础心血管疾病及主观整体评估评分)、用药情况(阿司匹林)、实验室检测指标(白蛋白、葡萄糖、碱性磷酸酶以及对数转换后的高敏C反应蛋白)以及超声心动图表现(左心室质量指数与左心室射血分数)。*心血管复合终点会依次校正以下变量:人口学特征(年龄、收缩压、糖尿病与基础心血管疾病)、用药方案(阿司匹林、氯吡格雷、维生素D及促红细胞生成剂)、实验室检测指标(钙、葡萄糖、钾、对数转换后的铁蛋白以及对数转换后的高敏C反应蛋白)以及超声心动图表现(左心室质量指数与左心室射血分数)。*全因死亡率会依次校正以下变量:人口学特征(体质量指数、查尔森合并症指数及主观整体评估评分)、用药方案(阿司匹林、氯吡格雷与维生素D)、实验室检测指标(碱性磷酸酶、钙、葡萄糖、对数转换后的铁蛋白以及对数转换后的高敏C反应蛋白)以及超声心动图表现(左心室质量指数与左心室射血分数)。缩写说明:TSAT(转铁蛋白饱和度,transferrin saturation);CV(心血管,cardiovascular);HR(风险比,hazard ratio);CI(置信区间,confidence interval)



