Genome-wide identification of rat long non-coding RNAs

In the current study, we have focused on a distinct group of non-coding elements, lncRNA, and profiled renal tissues from three different inbred rat strains. We chose the three strains S, SHR and R for the main purpose of cataloging lncRNA annotations from the most widely used rat models of cardiovascular and renal disease.本研究聚焦于一类独特的非编码元件——长链非编码RNA（long non-coding RNA, lncRNA），并对3种不同近交系大鼠品系的肾脏组织开展了表达谱分析。我们选取S、SHR与R这3个品系，核心目标是为当前应用最为广泛的心血管与肾脏疾病大鼠模型编目lncRNA注释信息。