ROC_all SINTEF workflow results with CASCADE topology
收藏资源简介:
This dataset has the input data + result dataset that was the product of using the <strong>DrugLogics</strong> computational pipeline with the <strong>rbbt</strong> workflow system to predict synergistic drug combinations across 8 cell lines that were also tested in SINTEF. The <strong>CASCADE topology</strong> was used and the logical models were trained to a <strong>steady state activity profile </strong>that was derived using the <strong>PARADIGM tool</strong> and input from the<strong> CCLE</strong>.
本数据集包含输入数据与结果数据集,该数据集系通过**DrugLogics**计算管线(computational pipeline)结合**rbbt**工作流系统(workflow system),针对8种已在SINTEF中完成实验测试的细胞系(cell lines)预测协同药物组合(synergistic drug combinations)所生成的产物。本次分析采用**CASCADE拓扑(CASCADE topology)**,并将逻辑模型训练至基于**PARADIGM工具(PARADIGM tool)**推导得到、且以**CCLE**数据作为输入的稳态活性谱(steady state activity profile)。



