GI SPORE Colon Biosample Protocol

The investigators are creating a data and specimen repository to study causes , early detection, prevention and treatment of colon and rectal cancer. The investigators are collecting data and specimens (blood, stool, urine and tissue) from people who have colon or rectal cancer, or who are risk for developing colorectal cancer or had normal colonoscopies. Data and samples are held in the repository until there are enough to be used for a large study or until there are new techniques that can be used to test them. The GI SPORE Program at the University of Michigan maintains a repository of specimens for colorectal diseases that the investigators hope will help fuel new research. The investigators hope that this work may lead to new treatments or earlier detection of colorectal cancer or improved diagnosis and treatment of other colon and rectal diseases.

本研究团队正在构建一套数据与标本库，用于探究结直肠癌（colon and rectal cancer）的致病原因、早期检测手段、预防措施及治疗方案。研究团队将从结直肠癌患者、结直肠癌发病高风险人群以及结肠镜检查（colonoscopy）结果正常的人群中采集数据与标本（血液、粪便、尿液及组织样本）。本数据与标本库将留存相关数据及样本，直至其规模足以支撑大规模研究，或出现可用于样本检测的新技术。密歇根大学胃肠道肿瘤专项研究计划（GI SPORE Program）目前维护有一套结直肠疾病相关标本库，本研究团队期望该库能够助力创新研究的开展。本研究团队期望本项目能够推动结直肠癌新型治疗方案的研发、早诊早筛的实现，或是改善其他结直肠疾病的诊断与治疗水平。