DAP-seq analysis of the transcription factor AaSom1 of Alternaria alternata tangerine pathotype, Sep 19 '25

In this study, DAP-seq was used to examine the DNA-protein interactions of the transcription factor AaSom1 in Alternaria alternata tangerine pathotype. By applying DIP-seq, we identified the genome-wide binding sites of AaSom1 within the mycelium and mapped the associated regulatory regions involved in fungal development and pathogenicity

本研究采用DAP-seq（DNA亲和纯化测序）技术，针对链格孢菌柑橘致病型（Alternaria alternata tangerine pathotype）中的转录因子AaSom1，对其DNA-蛋白质相互作用进行检测。随后，本研究借助DIP-seq（DNA免疫沉淀测序）技术，在该菌的菌丝体中鉴定出AaSom1的全基因组结合位点，并绘制出与真菌发育及致病性相关的调控区域图谱。