Additional file 8: of Genome analysis of E. coli isolated from Crohn’s disease patients

Comparison of the OG content of CD-isolates and commensal strains. Columns: OG – orthologous group number; Function – orthologous group function; gene group / global function – function of the operon or a major pathway in which OG participates; crohnall.yes − number of genomes from CrohnAll group containing the OG; crohnall.no − number of genomes from CrohnAll group not containing the OG; commensal.yes − number of genomes from commensal group containing the OG; commensal.no − number of genomes from commensal group not containing the OG; pvalues – Fisher’s test p-value; pvalues.adj – p-value after Holm’s adjustment; CD% / commensal % = % of CD genomes containing the subject OG divided by % of commensal strains containing the subject OG. (XLS 1813 kb)

克罗恩病（CD）分离菌株与共生菌株的直系同源簇（orthologous group，OG）内容比较。各列含义如下：OG——直系同源簇编号；Function——直系同源簇功能；gene group / global function——该OG所参与的操纵子功能或其所属的主要通路功能；crohnall.yes——CrohnAll组中携带该OG的基因组数量；crohnall.no——CrohnAll组中未携带该OG的基因组数量；commensal.yes——共生菌株组中携带该OG的基因组数量；commensal.no——共生菌株组中未携带该OG的基因组数量；pvalues——费希尔精确检验P值；pvalues.adj——经霍尔姆（Holm）校正后的P值；CD% / commensal %——携带目标OG的克罗恩病基因组占比与携带目标OG的共生菌株基因组占比的比值。（文件格式为XLS，大小1813 KB）