CK-3Y

CK-3Y investigates the impact of Lactobacillus <i>acidophilus</i> treatment on the gut microbiota in Clostridioides difficile infection. Fecal samples from mice post-infection were processed using Invitrogen with sequencing on the Ion Torrent NGS System. Analysis via Ion Reporter SW (16S) revealed shifts in microbial taxa dynamics over days 1, 3, and 6, shedding light on the potential of probiotics in modulating gut microbiota during C. difficile infection.The identification of the sample CK-3Y:<br>C: Denotes the strain ST-2 of Clostridioides difficile.<br>K: Represents timepoint 3, indicating sampling after treatment.<br>3: Refers to the specific mouse number under investigation.<br>Y: Indicates the treatment administered, which in this case is Lactobacillus <i>acidophilus</i>.

CK-3Y数据集探究了嗜酸乳杆菌(Lactobacillus acidophilus)干预对艰难梭菌(Clostridioides difficile)感染小鼠肠道菌群的影响。感染后小鼠的粪便样本经Invitrogen处理后，在Ion Torrent下一代测序(NGS)系统上完成测序。通过Ion Reporter SW（16S测序分析模块）开展的分析显示，在感染后第1、3、6天，微生物类群的动态变化特征出现显著偏移，该结果揭示了益生菌在艰难梭菌感染期间调节肠道菌群的潜在应用价值。
该样本CK-3Y的命名含义如下：
C：代表艰难梭菌菌株ST-2；
K：表示时间节点3，即干预给药后的采样时点；
3：指代本次研究中的特定受试小鼠编号；
Y：表示本次施加的干预手段，本案例中为嗜酸乳杆菌(Lactobacillus acidophilus)干预。