Transcriptome sequencing of Serpine1-overexpression MLE-12 cells. Transcriptome sequencing of Serpine1-overexpression MLE-12 cells

To determine the function of Serpine1 in alveolar cells, the Serpine1 overexpression plasmid pCI-neo-Serpine1 was constructed and transfected into MLE-12 cells Overall design: Comparative gene expression profiling analysis of RNA-seq data for Serpine1-overexpression MLE-12 cells

为阐明丝氨酸蛋白酶抑制剂E1（Serpine1）在肺泡细胞中的功能，本研究构建了Serpine1过表达质粒pCI-neo-Serpine1，并将其转染至MLE-12细胞中。实验整体设计：针对过表达Serpine1的MLE-12细胞的RNA测序（RNA-seq）数据开展比较基因表达谱分析。