Gene expression profiling of prostate basal cells at proximal and distal ducts. Gene expression profiling of prostate basal cells at proximal and distal ducts

We have noticed that the proliferative potential of epithelial cells in the mouse proximal prostatic ducts is less than those at the distal prostatic ducts. To determine whether specific signaling is differentially activated in distal and proximal prostate basal cells, we isolated respective basal cells in the two regions and performed an RNA-seq analysis. Overall design: Two group comparison

我们注意到，小鼠前列腺近端导管上皮细胞的增殖潜能低于远端导管上皮细胞。为明确特异性信号在前列腺远端与近端基底细胞中是否存在差异激活现象，我们分离了两个区域的对应基底细胞并进行了RNA测序（RNA-seq）分析。整体实验设计：两组对照。