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INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z30620520

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Protein Data Bank Japan2026-02-18 更新2026-03-21 收录
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INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z30620520 Descriptor: DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, cyclopropyl-[4-(4-fluorophenyl)piperazin-1-yl]methanone Authors: Bradshaw, W.J, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. Deposit date: 2020-10-30 Release date: 2020-11-11 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2. Structure, 2024

INPP5D PanDDA分析组存档——SHIP1磷酸酶结构域与C2结构域结合Z30620520的晶体结构 描述:二甲基亚砜(DIMETHYL SULFOXIDE)、磷脂酰肌醇3,4,5-三磷酸5-磷酸酶1(Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1)、环丙基-[4-(4-氟苯基)哌嗪-1-基]甲酮(cyclopropyl-[4-(4-fluorophenyl)piperazin-1-yl]methanone) 作者:Bradshaw, W.J、Newman, J.A、von Delft, F、Arrowsmith, C.H、Edwards, A.M、Bountra, C、Gileadi, O. 存档日期:2020-10-30 发布日期:2020-11-11 最后修改日期:2026-02-18 实验方法:X射线衍射(1.45 Å) 引用文献:《SHIP1与SHIP2的C2结构域调控肌醇5-磷酸酶活性》,《Structure》,2024年
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2020-10-30
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