Single-cell transcriptomics reveals microglia heterogeneity across the nigrostriatal pathway

Identification of specific microglia phenotypes within the nigrostriatal pathway, which may be relevant in PD Single cell mRNA of wild type (WT) mice, midbrain and striatum, were generated by Dropseq.

本数据集旨在获取黑质纹状体通路（nigrostriatal pathway）内特定小胶质细胞表型（microglia phenotypes）的鉴定数据，此类表型可能与帕金森病（Parkinson's disease，PD）相关。数据集通过Drop-seq（Dropseq）技术对野生型（WT）小鼠的中脑及纹状体组织进行单细胞mRNA测序而获得。