OstemiR expression pattern and predicted targets.

From the expression patterns of miRNA, actions and target mRNA were expected. Target genes in Homo sapiens were predicted by using TargetScan 5.2. Bone-, stemness-, epigenetics and cell-cycle-related target mRNAs were selected and shown. *miR-16 and miR-322/424 share targets.

基于微小RNA（miRNA）的表达谱，可推断其作用机制及靶信使RNA（mRNA）。本研究利用TargetScan 5.2预测了智人（Homo sapiens）的靶基因，筛选并展示了骨相关、干细胞干性、表观遗传学及细胞周期相关的靶mRNA。* miR-16与miR-322/424共享靶基因。