Cancer Moonshot Biobank - Invasive Breast Carcinoma Cancer Collection (CMB-BRCA)

The Cancer Moonshot Biobank is a National Cancer Institute initiative to support current and future investigations into drug resistance and sensitivity and other NCI-sponsored cancer research initiatives, with an aim of improving researchers' understanding of cancer and how to intervene in cancer initiation and progression. During the course of this study, biospecimens (blood and tissue removed during medical procedures) and associated data will be collected longitudinally from at least 1000 patients across at least 10 cancer types, who represent the demographic diversity of the U.S. and receiving standard of care cancer treatment at multiple NCI Community Oncology Research Program (NCORP) sites.

This collection contains de-identified radiology and histopathology imaging procured from subjects in NCI’s Cancer Moonshot Biobank - Invasive Breast Carcinoma Cancer (CMB-BRCA) cohort. Associated genomic, phenotypic and clinical data will be hosted by The Database of Genotypes and Phenotypes (dbGaP) and other NCI databases.

癌症登月计划生物样本库（Cancer Moonshot Biobank）是美国国家癌症研究所（National Cancer Institute, NCI）发起的一项倡议，旨在支持当前及未来针对药物耐药性、敏感性及其他由NCI资助的癌症研究项目，以提升研究者对癌症的认知，以及干预癌症发生与发展的手段。本研究将纵向收集至少10种癌症类型、超1000名患者的生物样本（医疗操作中获取的血液与组织样本）及关联数据，这些患者涵盖美国人口统计多样性，且在多个NCI社区肿瘤研究项目（NCI Community Oncology Research Program, NCORP）站点接受标准癌症治疗。

本次数据集包含从NCI癌症登月计划生物样本库——侵袭性乳腺癌（CMB-BRCA）队列受试者处获取的去标识化放射学与组织病理学成像数据。相关基因组、表型及临床数据将由基因型与表型数据库（Database of Genotypes and Phenotypes, dbGaP）及其他NCI数据库托管。