Summary statistic of a Trans ancestry multi-trait GWAS
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Trans ancestry multi-trait GWAS by adapting the omnibus test to the trans ancestry setting. Genome wide summary statistics for 19 blood count traits were retrieved from Chen et al paper and were downloaded from the GWAS Catalog (https://www.ebi.ac.uk/gwas/publications/32888493#study_panel) They curated using the JASS (Joint Analysis of Summary Statistics) pipeline https://gitlab.pasteur.fr/statistical-genetics/jass_suite_pipeline See Troubat et al preprint for all details on the obtention of this dataset https://doi.org/10.1101/2023.06.23.546248
本数据集基于将综合检验(omnibus test)适配至跨祖先场景的方法,开展了跨祖先多性状全基因组关联分析(GWAS, Genome-Wide Association Study)。19种血细胞计数性状的全基因组汇总统计数据取自Chen等人的研究论文,并从全基因组关联分析目录(GWAS Catalog,https://www.ebi.ac.uk/gwas/publications/32888493#study_panel)下载获得。该数据集通过JASS(汇总统计联合分析,Joint Analysis of Summary Statistics)流程完成整理与校验,相关流程的开源地址为https://gitlab.pasteur.fr/statistical-genetics/jass_suite_pipeline。有关本数据集获取的全部细节,请参阅Troubat等人的预印本文章:https://doi.org/10.1101/2023.06.23.546248。



