Olfactory neurotoxicity the tobacco cutworm moth after exposure to volatile organophosphorus pesticide dichlorvos

With the widespread use of volatile organophosphorus pesticides (OPs), air pollution and damage to the human and insect olfactory systems have attracted attention, but little is known about the mechanisms of olfactory neurotoxicity. This study aims to use the tobacco cutworm moth (Spodoptera litura) as a model to understand the mode of action of volatile dichlorvos-induced olfactory dysfunction. RNA-Sequencing was performed in the antenna and head of the the tobacco cutworm moth.

随着挥发性有机磷农药（volatile organophosphorus pesticides, OPs）的广泛应用，其造成的大气污染以及对人类与昆虫嗅觉系统的损伤已引发学界关注，但目前针对嗅觉神经毒性的作用机制仍知之甚少。本研究以斜纹夜蛾（Spodoptera litura）为模式生物，旨在探究挥发性敌敌畏诱导嗅觉功能障碍的作用机制。研究对斜纹夜蛾的触角与头部组织开展了RNA测序（RNA-Sequencing）。