Combinatorial role of Jmjd2b and Jmjd2c in mESCs identity

Genome-wide occupancy of biotinylated Jmjd2b, Jmjd2c from mESCs, as well as occupancy of selected factors and histone marks from wild-type mESCs, Anti-GFP KD, Jmj2b KD and Jmjd2c KD mESCs genome To identify genome-wide binding target sites of Jmjd2b and Jmjd2c in the mESCs genome, and genome-wide binding sites for selected factors and histone marks from Anti-GFP KD, Jmjd2b KD and Jmjd2c KD mESCs

本数据集包含从小鼠胚胎干细胞（mouse embryonic stem cells, mESCs）中获取的生物素标记Jmjd2b、Jmjd2c的全基因组结合占据谱，同时涵盖野生型mESCs、GFP靶向敲低（GFP knockdown, KD）、Jmjd2b敲低（Jmjd2b KD）及Jmjd2c敲低（Jmjd2c KD）mESCs中选定因子与组蛋白修饰的全基因组结合占据谱；本研究旨在鉴定mESCs基因组内Jmjd2b与Jmjd2c的全基因组结合靶位点，以及GFP靶向敲低、Jmjd2b敲低和Jmjd2c敲低mESCs中选定因子与组蛋白修饰的全基因组结合位点。