Data_Sheet_1_Metacognitive Treatment in Acquired Brain Injury and Its Applicability to Aphasia: A Systematic Review.docx

PurposeThe purpose of this systematic review is to identify the utility of metacognitive therapeutic intervention for persons with acquired brain injury (ABI), with a focus on persons with aphasia.
MethodsA search of six databases resulted in two hundred and sixty-six unique manuscripts relating to the explicit use of metacognitive treatment for people with ABI. Two independent reviewers rated abstracts for inclusion or exclusion of the study given predetermined criteria. Twenty-nine articles, five of which included people with aphasia, were selected for inclusion in this systematic review. SCED+ and PEDro+ rating scales were used to rate the methodological quality of each study.
ResultsMethodological quality of the 29 studies that met inclusion criteria ranged from weak to high quality studies. Three -hundred and sixty-nine individuals with ABI took part in the 29 studies. Varying treatment methods were employed. Outcome measures were inconsistent. Metacognitive treatment has been applied to people with aphasia with positive results, but efficacy of the treatment cannot yet be determined.
ConclusionsMetacognitive therapeutic intervention tends to be effective for persons with acquired brain injury (ABI) despite variability between intervention designs and treatment outcomes across studies. Due to so few studies with participants with aphasia, we were unable to draw conclusions regarding the efficacy of metacognitive treatment for people with aphasia. Further research on the efficacy of metacognitive treatment for this population is warranted.

研究目的：本项系统综述旨在明确元认知治疗干预对获得性脑损伤（acquired brain injury, ABI）患者的应用价值，重点聚焦失语症人群。
研究方法：通过检索6个数据库，共获得266篇与获得性脑损伤患者元认知治疗显性应用相关的独立文献。两名独立评审员依据预设标准对文献摘要进行纳入与排除评级，最终纳入29篇文献，其中5篇研究对象包含失语症患者。本研究采用SCED+与PEDro+评分量表对每项研究的方法学质量进行评分评级。
研究结果：符合纳入标准的29项研究，其方法学质量跨度从低等到高等不等。29项研究共纳入369名获得性脑损伤患者，所采用的治疗方案存在差异，结局测量指标也缺乏统一性。元认知治疗已应用于失语症患者并取得积极效果，但目前仍无法确定该治疗的临床有效性。
研究结论：尽管各项研究的干预设计与治疗结局存在异质性，但元认知治疗干预对获得性脑损伤患者整体呈现出良好的应用效果。由于涉及失语症患者的相关研究数量极少，本研究无法就元认知治疗针对该人群的有效性得出明确结论，未来仍需开展相关研究以明确其疗效。