Canonical nucleosome organization at promoters forms during genome activation

ChEBI2013-10-18 更新2026-07-21 收录

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染色质结构

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-44269 数据链接链接失效反馈

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Canonical nucleosome organization at promoters forms during genome activation

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2013-10-18

Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation

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In this study, our results support a functional divergence between H3K36me2 and H3K36me3 and their non-redundant roles in H3K36M-driven oncogenesis Overall design: 17 ChIP-seq samples, 3 RNA-seq sampl

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DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

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Epigenetic basis for monocyte dysfunction in acute-on-chronic liver failure and alcoholic hepatitis [RNA-seq]

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BACKGROUND/ AIMS: Severe forms of alcoholic liver disease are associated with increased susceptibility to infections largely due to immune dysfunction. In this study, we analyze the phenotypic, molecu

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Skeletal muscle is a metabolically active organ, but it remains largely unexplored in obesity. Here, we used diet-induced mice as obesity model to investigate the effect of obesity on muscle transcrip

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Canonical nucleosome organization at promoters forms during genome activation

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