Underlying dataset for the manuscript titled "Identification of RTS,S/AS01 vaccine-induced humoral biomarkers predictive of protection against controlled human malaria infection"

The antibody binding data included in this dataset is associated with the manuscript “Spreng, R.L., Seaton, K.E. et al., Identification of RTS,S/AS01 vaccine-induced humoral biomarkers predictive of protection against controlled human malaria infection; Accepted for Publication in JCI Insight (2024). These data come from the characterization of serum samples from four controlled human malaria infection (CHMI) clinical trials of the RTS,S vaccine, including NCT01366534 (referred to as MAL068), NCT01857869 (referred to as MAL071), NCT03162614 (referred to as MAL092), and NCT03824236 (referred to as MAL102).本数据集收录的抗体结合数据关联于论文《Spreng, R.L.、Seaton, K.E.等：鉴定RTS,S/AS01疫苗诱导的可预测受控人体疟疾感染（controlled human malaria infection, CHMI）防护效力的体液生物标志物》，该论文已被《JCI Insight》接收并将于2024年正式发表。本数据集的相关数据源于对RTS,S疫苗的四项受控人体疟疾感染（CHMI）临床试验的血清样本表征鉴定，涉及的临床试验注册号分别为NCT01366534（简称MAL068）、NCT01857869（简称MAL071）、NCT03162614（简称MAL092）以及NCT03824236（简称MAL102）。