The Influence of Preeclampsia, Advanced Maternal Age and Maternal Obesity in Neonatal Outcomes Among Women with Gestational Diabetes

Abstract Objective The present study aims to analyze adverse fetal or neonatal outcomes in women with gestational diabetes, including fetal death, preterm deliveries, birthweight, neonatal morbidity and mortality, as well as the synergic effect of concomitant pregnancy risk factors and poor obstetric outcomes, as advanced maternal age, maternal obesity and pre-eclampsia in their worsening. Methods The present cohort retrospective study included all pregnant women with gestational diabetes, with surveillance and childbirth at the Hospital da Senhora da Oliveira during the years of 2017 and 2018. The data were collected from the medical electronic records registered in health informatic programs Sclinico and Obscare, and statistical simple and multivariate analysis was done using IBM SPSS Statistics. Results The study participants included 301 pregnant women that contributed to 7.36% of the total institution childbirths of the same years, in a total of 300 live births. It was analyzed the influence of pre-eclampsia coexistence in neonatal morbidity (p = 0.004), in the occurrence of newborns of low and very low birthweight (p

【摘要】研究目标：本研究旨在分析妊娠糖尿病（gestational diabetes）孕妇的不良胎儿或新生儿结局，涵盖胎儿死亡、早产、出生体重异常、新生儿发病率与死亡率，同时探讨伴随妊娠危险因素（如产妇高龄、产妇肥胖及子痫前期（pre-eclampsia））与不良产科结局间的协同效应，及其对不良结局恶化的影响。
方法：本回顾性队列研究纳入2017至2018年间，在奥利维拉圣母医院（Hospital da Senhora da Oliveira）接受产前监护与分娩的所有妊娠糖尿病孕妇。研究数据取自健康信息程序Sclinico与Obscare中登记的电子病历，采用IBM SPSS Statistics软件完成单因素与多因素统计分析。
结果：本研究共纳入301名孕妇，占同期该院总分娩量的7.36%，共计活产300例。分析显示，合并子痫前期可显著影响新生儿发病率（p = 0.004），亦可影响低出生体重儿与极低出生体重儿的发生率（p =