Crystal structure of Phosphite Dehydrogenase mutant I151R/P176E from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine dinucleotide

Crystal structure of Phosphite Dehydrogenase mutant I151R/P176E from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine dinucleotide Descriptor: Phosphite dehydrogenase, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate Authors: Song, X, Feng, Y, Liu, Y, Zhao, Z. Deposit date: 2018-09-28 Release date: 2019-03-13 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.468 Å) Cite: Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor Acs Catalysis, 9, 2019

来自拉尔斯顿氏菌属（Ralstonia sp.）4506的磷酸脱氢酶（Phosphite Dehydrogenase）突变体I151R/P176E与非天然辅酶烟酰胺胞嘧啶二核苷酸（Nicotinamide Cytosine dinucleotide）结合形成复合物的晶体结构。描述：磷酸脱氢酶，配体为[[(2S,3S,4R,5S)-5-(3-氨基甲酰吡啶鎓-1-基)-3,4-二羟基四氢呋喃-2-基]甲氧基-膦酰氧基] [(2S,3S,4R,5S)-5-(4-氨基-2-氧代嘧啶-1-基)-3,4-二羟基四氢呋喃-2-基]甲基氢磷酸酯。作者：Song, X、Feng, Y、Liu, Y、Zhao, Z。存放日期：2018-09-28。发布日期：2019-03-13。最后修改日期：2024-03-27。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.468埃（Å）。引用：《青睐非天然氧化还原辅酶的磷酸脱氢酶变体的结构解析》，发表于《ACS催化（ACS Catalysis）》，第9卷，2019年。