Expression data of GMP and MDP from wild-type and Trib1-/- mice

Trib1 is critical for some myeloid cell differentiation. Therefore we used microarrays to investigate gene expression profiles in wild-type and Trib1-/- progenitor of myeloid cells. Progenitor cells, such as GMP and MDP, obtained from wild-type and Trib1-/- mice were sorted, followed by RNA extraction. Then hybridization on affymetrix microarrays was performed.

Trib1 对部分髓系细胞分化至关重要。为此，我们采用基因芯片（microarrays）技术，对野生型与Trib1基因敲除（Trib1-/-）小鼠的髓系细胞祖细胞基因表达谱展开研究。我们从野生型及Trib1-/-小鼠中分选得到粒细胞-巨噬细胞祖细胞（Granulocyte-Macrophage Progenitor，GMP）、巨噬细胞树突状细胞祖细胞（Macrophage-Dendritic Progenitor，MDP）等祖细胞，随后提取RNA，继而在Affymetrix基因芯片上完成杂交反应。