Effects of desensitizing products on the reduction of pain sensitivity caused by in-office tooth bleaching: a 24-week follow-up

Abstract Objective To clinically assess the effect of desensitizing gels and dentifrices on the reduction in pain sensitivity and color variation during tooth bleaching. Methodology A total of 108 volunteers were randomly separated into the following groups of n=12: GT/S-glycerine and thickener/sucralose; NF/S-potassium nitrate and sodium fluoride/sucralose; NA/S-potassium nitrate and arginine/sucralose; GT/AC-glycerine and thickener/arginine and calcium carbonate; NF/AC-potassium nitrate and sodium fluoride/arginine and calcium carbonate; NA/AC-potassium nitrate and arginine/arginine and calcium carbonate; GT/PN-glycerine and thickener/potassium nitrate; NF/PN-potassium nitrate and sodium fluoride/potassium nitrate; and NA/PN-potassium nitrate and arginine/potassium nitrate. Sensitivity was assessed with the numerical analogue scale, and color variation (ΔE) was measured with a spectrophotometer. The sensitivity values obtained were subjected to a multivariate analysis of variance (MANOVA) and color variation values were subjected to a randomized analysis of variance (p

【摘要】 研究目的：临床评估脱敏凝胶与洁齿剂在牙齿漂白过程中对疼痛敏感性降低及色泽变化的影响。研究方法：共计108名志愿者被随机分为9组，每组样本量n=12，各组设置如下：GT/S组：甘油与增稠剂/三氯蔗糖；NF/S组：硝酸钾与氟化钠/三氯蔗糖；NA/S组：硝酸钾与精氨酸/三氯蔗糖；GT/AC组：甘油与增稠剂/精氨酸与碳酸钙；NF/AC组：硝酸钾与氟化钠/精氨酸与碳酸钙；NA/AC组：硝酸钾与精氨酸/精氨酸与碳酸钙；GT/PN组：甘油与增稠剂/硝酸钾；NF/PN组：硝酸钾与氟化钠/硝酸钾；NA/PN组：硝酸钾与精氨酸/硝酸钾。疼痛敏感性采用数字类比量表（Numerical Analogue Scale）进行评估，色泽变化（ΔE）通过分光光度计（Spectrophotometer）进行测量。所得疼痛敏感性数据采用多变量方差分析（Multivariate Analysis of Variance, MANOVA）进行统计处理，色泽变化数据则采用随机方差分析（Randomized Analysis of Variance）（p