Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers

Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers Descriptor: 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', CALCIUM ION, ... Authors: Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G. Deposit date: 2007-09-14 Release date: 2008-10-28 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases Nature, 456, 2008

工程化归巢核酸酶（engineered homing endonuclease）异二聚体识别并切割人类XPC基因的分子基础
描述符：5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', 钙离子（CALCIUM ION）等
作者：Redondo, P、Prieto, J、Muñoz, I.G、Alibes, A、Stricher, F、Serrano, L、Arnould, S、Perez, C、Cabaniols, J.P、Duchateau, P、Paques, F、Blanco, F.J、Montoya, G
存档日期：2007-09-14
发布日期：2008-10-28
最后修改日期：2023-12-13
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.95埃（Å）
引用文献：《工程化大范围核酸酶（meganuclease）识别着色性干皮病（Xeroderma Pigmentosum）C组DNA的分子基础》，《自然（Nature）》，第456卷，2008年