X-ray crystal structure of beta secretase complexed with compound 7

X-ray crystal structure of beta secretase complexed with compound 7 Descriptor: Beta-secretase 1, DIMETHYL SULFOXIDE, IODIDE ION, ... Authors: Patel, S. Deposit date: 2007-01-10 Release date: 2007-03-13 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase. J.Med.Chem., 50, 2007

与化合物7结合的β分泌酶（beta secretase）X射线晶体结构。表征项：β分泌酶1（Beta-secretase 1）、二甲基亚砜（DIMETHYL SULFOXIDE）、碘离子（IODIDE ION）……作者：S·帕特尔（Patel, S.）。提交日期：2007-01-10；发布日期：2007-03-13；最后修改日期：2024-11-06。实验方法：X射线衍射法（X-RAY DIFFRACTION），解析分辨率为2.3埃（2.3 Å）。引用文献：《X射线晶体学片段筛选在β分泌酶抑制剂氨基吡啶类化合物发现中的应用》（Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase），刊载于《J.Med.Chem.》，2007年，第50卷。