Dutch ADE corpus

The corpus contains 102 anonymised Dutch Intensive Care progress notes with 16,470 labels, consisting of 8,914 Disorder entities, 5,307 Drug entities, 134 Qualitative Concept entities, 1,501 Indication relations, and 614 Adverse Drug Event (ADE) relations. Annotation reached high agreement for all entities (F1 score 0.7724) with an expected lower agreement for relations (F1 score 0.4327). The Dutch ADE corpus is a real-world data set that can be used to evaluate natural language processing pipelines for ADE detection tasks. Although the corpus was developed for drug-related acute-kidney injury, 158 additional ADEs were identified. The combination of iterative annotation guideline development and double annotation followed by adjudication produced high quality annotations.Re-use of the Dutch ADE Corpus is possible upon reasonable request and subject to certain limitations. Access requests and terms of use can be found here.Please use the following citation to give the authors credit for their work, should you use or refer to the Dutch ADE Corpus: Murphy, R.M., Dongelmans, D.A., de Keizer, N.F. et al. Creation of a gold standard Dutch corpus of clinical notes for adverse drug event detection: the Dutch ADE corpus. Lang Resources & Evaluation (2025). https://doi.org/10.1007/s10579-025-09832-5

本语料库包含102份已匿名化的荷兰语重症监护病程记录，共计16470个标注标签，涵盖8914个病症实体（Disorder entities）、5307个药物实体（Drug entities）、134个定性概念实体（Qualitative Concept entities）、1501个适应症关系（Indication relations）以及614个药物不良反应（Adverse Drug Event, ADE）关系。所有实体类别的标注均达到了较高的一致性（F1值为0.7724），而关系类别的标注一致性则相对较低（F1值为0.4327）。荷兰语ADE语料库属于真实世界数据集，可用于评估面向药物不良反应检测任务的自然语言处理流水线。尽管该语料库最初是为药物相关性急性肾损伤研究开发的，但最终额外识别出了158例药物不良反应案例。通过迭代制定标注指南，并采用双标注后经复核裁定的标注流程，最终生成了高质量的标注结果。可通过合理申请并遵守相关限制条件，复用该荷兰语ADE语料库。访问申请方式及使用条款可在此处查阅。若您使用或引用该荷兰语ADE语料库，请使用以下引用信息以表彰原作者的工作：Murphy, R.M., Dongelmans, D.A., de Keizer, N.F. 等. 用于药物不良反应检测的荷兰语临床笔记金标准语料库构建：荷兰语ADE语料库. Lang Resources & Evaluation (2025). https://doi.org/10.1007/s10579-025-09832-5