Ahuja_Lab_COVID_WB_Longitudinal_dataset_VA-CLC_phenotypes.csv

This file contains the phenotype characteristics of the corresponding gene expression dataset.Note: The samples used for analysis presented in Figs. 6G, 6H and figs. S29, S36, S44 are marked in the CSV.Criteria:Fig. 6G: Expression data within 14 days from IHG baseline of 46 participants (228 measurements) was used to determine the SAS-1/MAS-1 profiles and compared to concurrent IHG. IHG baseline is the date of the first available IHG for each participant. There were 2 non-hospitalized individuals with no RNA-Seq measurements within this time window.Fig. 6H: Expression data from RNA-Seq baseline of 48 participants was used to determine the SAS-1/MAS-1 profiles and compared to COVID-19 outcomes by 30-day survival status. RNA-Seq baseline is the date of the first available RNA-Seq data for each participant.Fig. S29: Only expression data within 7 days from IHG baseline of 45 participants was plotted by baseline IHG and COVID-19 outcomes by 30-day survival status. IHG baseline is the date of the first available IHG for each participant. There were 3 non-hospitalized individuals with no RNA-Seq measurements within this time window.Fig. S36: Only expression data from RNA-Seq baseline of 48 participants was to generate the plots and determine the SAS-1/MAS-1 profiles. COVID-19 outcomes was determined by 30-day survival status. RNA-Seq baseline is the date of the first available RNA-Seq data for each participant.Fig. S44: Only expression data from RNA-Seq baseline of 20 participants was to generate the pots of transcription factors by IHG status (IHG-1 vs. IHG-IIc/IVc). RNA-Seq baseline is the date of the first available RNA-Seq data for each participant.本文件收录对应基因表达数据集的表型特征。注：图6G、6H及补充图S29、S36、S44中用于分析的样本已在CSV文件中标记。 分析准则： 1. 图6G：纳入46名受试者在距间歇性低氧训练（IHG）基线14天内的表达数据（共228次检测结果），用于确定SAS-1/MAS-1分型，并与同期IHG状态进行对比。其中，IHG基线指每名受试者首次可获取的IHG检测日期；此时间窗内无RNA测序（RNA-Seq）检测数据的非住院受试者共2例。 2. 图6H：纳入48名受试者的RNA测序（RNA-Seq）基线表达数据，用于确定SAS-1/MAS-1分型，并依据30天生存状态对比其新型冠状病毒感染（COVID-19）转归。其中，RNA测序基线指每名受试者首次可获取的RNA测序数据日期。 3. 补充图S29：仅纳入45名受试者在距IHG基线7天内的表达数据，按IHG基线及30天生存状态下的COVID-19转归进行绘图。IHG基线定义同前；此时间窗内无RNA-Seq检测数据的非住院受试者共3例。 4. 补充图S36：仅纳入48名受试者的RNA测序基线表达数据用于绘图及确定SAS-1/MAS-1分型，并依据30天生存状态判定其COVID-19转归。RNA测序基线定义同前。 5. 补充图S44：仅纳入20名受试者的RNA测序基线表达数据，用于绘制按IHG状态（IHG-1 vs. IHG-IIc/IVc）分组的转录因子（transcription factors）图谱。RNA测序基线定义同前。