ATN 004 CAPI #7: Timeline Follow Back Substance Abuse: Substance Use Dates (3) Dataset in Healthy Choices: Motivational Enhancement to Promote Health and Reduce Risk in HIV-Infected Youth

Data from CAPI #7: Timeline Follow Back Substance Abuse: Substance Use Dates (3)
Study Description
In this Phase II multi-site clinical trial, HIV+ youth were randomized to receive either a four-session motivational enhancement intervention and referrals or standard care plus referrals. Participants randomized to the intervention group participated in four sessions of Healthy Choices, a motivational enhancement intervention specifically designed to target multiple risk behaviors in HIV+ youth. Participants received individualized referrals at the fourth session. Participants randomized to standard care also received individualized referrals. Interviews, self-report, chart review and blood tests were used to measure substance use, condom use, adherence to medications, and health outcomes, as well as hypothesized mediators and moderators of the intervention. The primary objective was to determine the efficacy of a motivational enhancement intervention in reducing health risk behaviors (drug and alcohol use, sexual risk behavior, poor adherence to medications) among HIV+ youth. HIV+ youth ages 16 to 24 years, engaged in two out of three problem behaviors (substance use, sexual risk behavior, or poor medication adherence)

CAPI #7数据集：时间线回溯法（Timeline Follow Back）物质滥用研究：物质使用日期（3）
研究概述
本项多中心Ⅱ期临床试验中，HIV阳性青年被随机分为两组：一组接受4次会话的动机强化干预（motivational enhancement intervention）及转介服务，另一组接受标准护理加转介服务。被随机分配至干预组的参与者需完成4次「健康选择（Healthy Choices）」课程，该课程为专门针对HIV阳性青年多重风险行为设计的动机强化干预方案。干预组与标准护理组的参与者均将在第4次课程时获得个性化转介服务。本研究通过访谈、自我报告、病历审查及血液检测，对物质使用、安全套使用、药物依从性、健康结局，以及该干预的预设中介变量与调节变量进行评估。本研究的主要目的为验证动机强化干预在降低HIV阳性青年健康风险行为（吸毒与饮酒、性风险行为、药物依从性不佳）方面的有效性。本研究的纳入对象为16至24岁的HIV阳性青年，且存在三类问题行为中的两类：物质使用、性风险行为或药物依从性不佳。