Luminal and mucosal microbiota in the duodenum and jejunum of Eimeria acervulina-infected and control broiler chickens

The aim of this study was to determine the effect of Eimeria acervulina infection on the luminal and mucosal microbiota in the duodenum and jejunum of broiler chickens at multiple time points during infection. The study demonstrates that luminal and mucosal bacterial populations differ in the duodenum and jejunum, making it important to understand both populations. Infections may have shorter or longer-term effects on microbiota diversity depending on luminal/mucosal and GIT region. Infection may also influence relative abundances of SCFA-producing bacteria in infected birds.

本研究旨在明确堆型艾美耳球虫（Eimeria acervulina）感染过程中多个时间点下，肉鸡十二指肠与空肠的腔道及黏膜微生物群所受的影响。本研究发现，肉鸡十二指肠与空肠内的腔道细菌菌群与黏膜细菌菌群存在显著差异，因此同时解析这两类菌群具有重要研究意义。感染对微生物群多样性的影响时长存在长短之分，具体取决于作用的组织层面为腔道/黏膜区域，还是胃肠道（gastrointestinal tract, GIT）区段。此外，感染还可影响受感染肉鸡体内产短链脂肪酸的细菌的相对丰度。