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Loci previously reported to colocalise with liver eQTL, but not supported by our analysis.

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Loci_previously_reported_to_colocalise_with_liver_eQTL_but_not_supported_by_our_analysis_/1027683
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Gene/eQTL associations previously reported as having a probable shared variant but not supported by our method based on PP3 (posterior probability for distinct signal values) >75%. *Secondary signals are reported only when there is a secondary eQTL at a p-value greater than . Colocalisation tests are computed using the expression data conditioned on the listed SNP. Other genes in the same region as the gene listed that colocalise using our method are reported.

此前被报道存在潜在共享变异的基因/表达数量性状位点(expression Quantitative Trait Locus, eQTL)关联,经本方法以PP3(区分不同信号的后验概率,posterior probability for distinct signal values)大于75%为标准评估后,未获得本方法的支持。 *仅当存在P值大于[原文此处缺失具体阈值]的次级eQTL时,才会报告次级信号。 共定位分析检验基于所列单核苷酸多态性(Single Nucleotide Polymorphism, SNP)条件校正的表达数据进行计算。 通过本方法检测到共定位的、与所列基因处于同一基因组区域的其他基因,亦将被纳入报告范围。
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2015-12-02
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