Expression data from isolated perfused rat hearts exposed to doxorubicin

We used microarrays to detail transcriptional changes in the rat heart in response to doxorubicin, a chemotherapeutic drug known to induce cardiac disfunction/heart failure Keywords: treatment vs control Langendorff perfusion of isolated hearts with/without doxorubicin

本研究采用基因芯片（microarrays）技术，详细解析了大鼠心脏在接触化疗药物阿霉素（doxorubicin）后的转录组变化；阿霉素是一种已知可诱发心功能异常/心力衰竭的化疗药物。关键词：处理组与对照组；Langendorff灌流（Langendorff perfusion）：对离体心脏分别施加阿霉素处理与空白对照处理。