Incidence of GVHD in each rs7588571 genotype.

Figshare2017-09-25 更新2026-04-29 收录

移植物抗宿主病机制

SNP-疾病关联分析

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Incidence of GVHD in each rs7588571 genotype.

各rs7588571基因型的移植物抗宿主病（Graft-versus-Host Disease, GVHD）发病率

创建时间：

2017-09-25

Modification of T cell responses by stem cell mobilization requires direct signalling of the T cell by G-CSF and IL-10. Mus musculus

移植免疫调节

移植物抗宿主病机制

The majority of allogeneic stem cell transplants are currently undertaken using G-CSF mobilized peripheral blood stem cells. G-CSF has diverse biological effects on a broad range of cells and IL-10 is

NIAID Data Ecosystem40

Proportion of mild malaria episodes according to rs2736191 polymorphism.

疟疾宿主遗传易感性

SNP-疾病关联分析

Proportion of mild malaria episodes according to rs2736191 polymorphism.

NIAID Data Ecosystem20

Steroid-resistant gut graft-versus-host disease results from expansion of Th/Tc22, dysbiosis, and depletion of CX3CR1hi phagocytes

移植物抗宿主病机制

肠道微生态

CD4+ and CD8+ T cells can reciprocally differentiate into Th/Tc1, Th/Tc17 and Th/Tc22. Although alloreactive Th/Tc1 cells play a critical role in initiating pathogenesis of gut acute graft-versus-host

NIAID Data Ecosystem10

Restricting SLC7A5-mediated Leucine uptake in T cells prevents acute GVHD and maintains GVT response (EMM-2024-19430)

免疫代谢

移植物抗宿主病机制

The L-Leu amino acid transporter SLC7A5 has become an important target in inflammation and cancer. However, its role in acute graft-versus-host disease (aGVHD) and graft versus tumor (GVT) remains une

NIAID Data Ecosystem20

Gene expression analysis of molecules with known function in HLA class II antigen processing and presentation in hematopoietic and (cytokine pre-treated) non-hematopoietic cells.

HLAII类抗原呈递基因表达

移植物抗宿主病机制

Gene expression analysis of molecules with known function in HLA class II antigen processing and presentation. Various hematopoietic cell types and (cytokine pre-treated) non-hematopoietic cells that

NIAID Data Ecosystem20

Incidence of GVHD in each rs7588571 genotype.

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