A Splice Variant of HER2 Activates Key Signaling Cascades and Evokes Mammary Tumors and Metastases

ChEBI2013-10-22 更新2026-07-21 收录

乳腺癌分子机制

HER2信号通路

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42781 数据链接链接失效反馈

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A Splice Variant of HER2 Activates Key Signaling Cascades and Evokes Mammary Tumors and Metastases

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2013-10-22

Differential expression in T47-D human breast cells after baiclalein treatment

乳腺癌分子机制

黄酮类化合物作用

Investigate differences in gene expresion profiles of T47-D human breast cancer cells when treated with baicalein. Gene expression profiling analysis from polyA RNA-seq of 2 replicates of T47-D cell

NIAID Data Ecosystem110

MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells.

HER2信号通路

乳腺癌脂筏微环境

The lipid raft resident protein, MAL2, has been implicated as contributing to the pathogenesis of several malignancies, including breast cancer, but the underlying mechanism for its effects on tumorig

NIAID Data Ecosystem50

Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.. Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.

乳腺癌分子机制

受体信号通路

Inhibitory crosstalk between estrogen receptor alpha (ER alpha ) and aryl hydrocarbon receptor (AHR) regulates 17-estradiol (E2)-dependent breast cancer cell signaling. ER alpha and AHR are transcript

NIAID Data Ecosystem40

Additional file 1: of Inferring miRNA sponge co-regulation of protein-protein interactions in human breast cancer

乳腺癌分子机制

RNA调控网络

BRCA-related miRNA sponge interaction network. The network includes 37076 miRNA sponge interactions. (XLSX 484Â kb)

NIAID Data Ecosystem70

The primer sequence.

乳腺癌分子机制

癌症药物靶点

BackgroundBreast cancer continues to be a predominant cause of female mortality globally, characterized by limited therapeutic options and substantial adverse effects. Artesunate (ART), a traditional

Figshare2025-08-04 更新40

A Splice Variant of HER2 Activates Key Signaling Cascades and Evokes Mammary Tumors and Metastases

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