Rattus norvegicus strain:Sprague-Dawley(SD) Raw sequence reads. Rattus norvegicus strain:Sprague-Dawley(SD)

In the present study, we used NGS to characterise lncRNA-seq of acute myocardial infarction (AMI) rats and healthy controls to elucidate the functions and mechanisms of lncRNAs in cardiomyocytes. We want to identified a certain pair of lncRNA and its binding mRNA to elucidate the role in ischemia-hypoxia cardiomyocytes for AMI.

本研究采用下一代测序（Next-Generation Sequencing, NGS）技术，对急性心肌梗死（acute myocardial infarction, AMI）模型大鼠与健康对照的长链非编码RNA测序（long non-coding RNA sequencing, lncRNA-seq）数据进行表征分析，以阐明长链非编码RNA（long non-coding RNA, lncRNA）在心肌细胞中的功能及作用机制。本研究旨在鉴定特定的lncRNA及其结合的信使RNA（messenger RNA, mRNA）配对，以解析二者在急性心肌梗死相关缺血缺氧心肌细胞中的调控作用。