Additional file 1 of Poliovirus immunity among adults in the Democratic Republic of the Congo: a cross-sectional serosurvey

Additional file 1: Table S1. Comparison of DRC 2013–2014 adult DHS respondent demographics across sample split. Table S2. To test for intra-household correlation in seropositivity, we merged the adult and child datasets, and assessed whether any child and/or any adult in the household was seropositive for each type of polio. The table below summarizes the results across households. Using Pearson’s Chi-squared test, we find that sero-status has a mild positive association for Type 2 (p = 0.01), but there is little evidence for within household correlation for Types 1 and 3. Figure S1. Study design flowchart for dried blood spot (DBS) sampling, testing, and analysis. From a total of 8713 DBS collected in the field, 5526 (63.4%) were successfully processed and merged to DHS questionnaire data for inclusion in this analysis.

附加文件1：表S1 2013–2014年刚果（金）成人人口与健康调查（Demographic Health Survey, DHS）受访者人口统计学特征在不同样本划分下的对比。表S2 为检验血清阳性结果的家庭内相关性，我们合并成人与儿童数据集，针对每型脊髓灰质炎，评估家庭内是否存在任意儿童和/或任意成人血清学呈阳性。下表汇总了各家庭的分析结果。采用皮尔逊卡方检验（Pearson’s Chi-squared test），结果显示2型脊髓灰质炎的血清学状态存在轻度正相关（p=0.01），但1型和3型脊髓灰质炎几乎无家庭内相关性的相关证据。图S1 干血斑（Dried Blood Spot, DBS）采样、检测与分析的研究设计流程图。本次研究野外共采集8713份干血斑样本，其中5526份（占比63.4%）成功完成实验处理，并与人口与健康调查问卷数据进行匹配合并，纳入本次分析。