Age structured models fail to predict population decay rates for cells treated with cisplatin.

Shown here are deviations (in %) of the predicted decay rates from the measured decay rates (obtained via linear regression of post-cisplatin experimental data in Fig 1b and 1e). Predictions were made using IMT and AT distributions obtained directly from the experiment (‘Measured’) and from competing risks-corrected unbiased distributions (‘Inferred’).

本内容展示了预测衰变率相较于实测衰变率的百分比偏差。其中实测衰变率通过对图1b与图1e中的顺铂处理后实验数据进行线性回归得到。本次预测分别采用了两类分布完成：一类为直接从实验中获取的IMT与AT分布，对应“实测”组；另一类为经竞争风险校正的无偏分布，对应“推断”组。