Functional Dissection of Variant Polycomb Repressive Complex 1 Subunits RYBP and YAF2 during Neural Differentiation of Embryonic Stem Cells [ATAC-Seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE213415
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ATAC-seq was used to investigate the impact of Rybp knockout on chromatin accessibility in 46C mESCs. Rybp-/- mESC lines were generated by using CRISPR/Cas9.
本研究采用转座酶可及性测序(ATAC-seq)技术,探究Rybp基因敲除对46C小鼠胚胎干细胞(mouse embryonic stem cells,mESCs)染色质可及性的影响。通过成簇规律间隔短回文重复序列相关蛋白9(CRISPR/Cas9)技术,研究者构建了Rybp-/-型46C小鼠胚胎干细胞系。
创建时间:
2024-01-08



