Map of DnaC localization in the presence or absence of PcrA (MycPcrA)

The replicative helicase, DnaC, was immunoprecipitated in cell extract prior to, or following conditional depletion of PcrA Overall design: The differential DnaC association at each genomic location was determined before/after PcrA depletion复制解旋酶（replicative helicase）DnaC在PcrA条件性敲减前后的细胞提取物中均被免疫沉淀。实验整体设计：本研究测定了PcrA条件性敲减前后，DnaC在各基因组位点的结合差异。