Association of depressive symptoms with impaired episodic memory in patients with Parkinson's disease

ABSTRACT Objective: To evaluate the correlation of depressive symptoms and impaired episodic memory in patients with Parkinson's disease (PD). Methods: This is a cross-sectional, non-probabilistic and intentional study. Individuals diagnosed with PD and aged 60 years or older, who were enrolled at two movement disorders outpatient clinics in the city of Maceió, AL, were selected. 62 elderly people were selected, divided into two groups, 40 with symptoms of depression and 22 without symptoms of depression. A sociodemographic questionnaire, Geriatric Depression Scale (GDS-15 reduced version), the Rey Auditory-Verbal Learning Test (RAVLT) and Montreal Cognitive Assessment (MoCA) were used. Results: In view of the sample of 62 elderly people, there was a high prevalence of female elderly, 64.5% with a mean age of 66.72 years (±5.12). Regarding sociodemographic data, a statistically significant difference was identified between groups only in the use of antidepressants (p

摘要 目的：评估帕金森病（Parkinson's disease, PD）患者的抑郁症状与情景记忆损害的相关性。方法：本研究为横断面、非概率目的性研究。研究对象为阿拉戈斯州马塞约市两家运动障碍门诊招募的确诊帕金森病且年龄≥60岁的老年人，最终纳入62名老年受试者，分为两组：伴抑郁症状组40例，无抑郁症状组22例。本研究采用社会人口学问卷、老年抑郁量表15项简版（Geriatric Depression Scale, GDS-15）、雷伊听觉语言学习测验（Rey Auditory-Verbal Learning Test, RAVLT）以及蒙特利尔认知评估量表（Montreal Cognitive Assessment, MoCA）进行测评。结果：62名老年受试者中，女性占比64.5%，平均年龄为66.72±5.12岁，女性受试者占比偏高。社会人口学特征分析显示，仅抗抑郁药物使用情况在两组间存在统计学差异（p