Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [BcorKrasRNA-seq]. Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [BcorKrasRNA-seq]

Investigation of the transcriptional profile of BcorΔE9-10KrasG12D myeloid progenitors Overall design: Splenocytes from BcorΔE9-10KrasG12D mice were transplanted into PTPRCA recipients, after 4 weeks donor-derived KL cells were isolated and RNA sequencing performed

本研究针对BcorΔE9-10KrasG12D髓系祖细胞的转录谱开展研究。实验整体设计：将BcorΔE9-10KrasG12D小鼠的脾细胞移植至PTPRCA受体小鼠体内，移植4周后分离供体来源的KL细胞并进行RNA测序（RNA sequencing）。