Improved reprogramming across multiple donors from a single vial of blood.

The table represents reprogramming trials beginning from a single vial of blood performed across a set of donors independent from Table 2. Set 1 refers to the two plasmid combination expressing C-myc and Set 2 involves the 3 plasmid combination set expressing L-myc. Asterisks indicate the generation of iPSCs from CD34+ cells isolated fresh from blood while all other trials were performed from CD34+ cells isolated from PBMCs that were frozen down immediately after isolation from blood. N indicates the number of single vial reprogramming trials performed for each donor. Reprogramming efficiencies were averaged where N>1.该表格展示了以单管血液样本为起始材料，针对独立于表2的一批供体开展的细胞重编程实验。其中，组1指代表达C-myc的双质粒联合体系，组2则为表达L-myc的三质粒联合体系。星号标注代表从新鲜分离自血液的CD34阳性细胞（CD34+ cells）中诱导生成诱导多能干细胞（induced pluripotent stem cells, iPSCs）；其余所有实验均使用从血液分离后即刻冻存的外周血单个核细胞（peripheral blood mononuclear cells, PBMCs）中分离得到的CD34阳性细胞。N代表针对每位供体开展的单管重编程实验次数；当N>1时，重编程效率取平均值。