Homology of the PP1c consensus binding motifs deduced from the AIF sequence in different species.

AIF proteins contain a putative PP1c docking sequence (R/K)x (0,1)V/IxFxx(R/K)x(R/K) which combines the two canonical PP1c docking motifs (R/K)x(0,1)V/IxF and Fxx(R/K)x(R/K) initially characterized in certain Bcl-2 proteins [1], [6].
Sequences are shown with a single letter code for amino acids, and residues corresponding to invariable amino acids in the PP1c site are in capital letters.

凋亡诱导因子蛋白（AIF proteins）含有一段推定的蛋白磷酸酶1催化亚基（PP1c）停靠序列，其序列为(R/K)x (0,1)V/IxFxx(R/K)x(R/K)；该序列整合了两种经典的PP1c停靠基序：(R/K)x(0,1)V/IxF与Fxx(R/K)x(R/K)，二者最初在部分Bcl-2蛋白（B-cell lymphoma 2 proteins）中被鉴定[1],[6].
序列采用氨基酸单字母缩写形式呈现，PP1c结合位点内对应保守氨基酸的残基以大写字母标注。