RNAseq of Normal Human Epidermal Keratinocytes (NHEKs) in UVB-induced senescence (UVB-SIPS, at 3 days or 5 days) or in replicative-like senescence (RS)

RNAseq analyses of NHEKs in replicative-like senescence, i.e. in growth arrest after about ten passages in culture, or in premature senescence induced by repeated UVB exposures (UVB-SIPS), at 3 days and at 5 days after the last UVB stress.

本数据集为针对正常人表皮角质形成细胞（Normal Human Epidermal Keratinocytes, NHEKs）的RNA测序（RNAseq）分析，所分析的细胞包含两类衰老状态：一类为类复制性衰老，即体外培养约10次传代后进入生长停滞状态的细胞；另一类为经重复紫外线B（UVB）照射诱导产生的应激早衰（UVB-induced Stress Premature Senescence, UVB-SIPS）细胞。所有样本均采集自末次UVB应激后的第3天与第5天。